From sequences to graphs: discrete methods and structures for bioinformatics

By: Chateau, Annie [Editor] | Salson, Mikael [Co-Editor]Material type: Text

TextLanguage: English Publication details: New Jersey: Wiley Data and Cybersecurity, 2022. Edition: 1st edDescription: xix, 243pISBN: 9781394169627Subject(s): Algorithmic Solutions of Bioinformatics Problems | Metagenomics and Metatranscriptomics | Sequence Alignment, Indexing and Genome AssemblyDDC classification: 574.88018 Online resources: Click here to access online

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Item type	Current library	Call number	Status	Date due	Barcode
e-Books	Dr. S. R. Ranganathan Library Ebook (Online Access)	574.88018 (Browse shelf(Opens below))	Available		EB0146

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In order to study living organisms, scientists not only study them at an overall macroscopic scale but also on a more detailed microscopic scale. This observation, pushed to its limits, consists of investigating the very center of each cell, where we find the molecules that determine the way it functions: DNA (deoxyribonucleic acid) and RNA (ribonucleic acid).

In an organism, DNA carries the genetic information, which is called the genome. It is represented as four-letter sequences using the letters A, C, G and T; based on these sequences, computer methods described in this book can answer fundamental questions in bioinformatics.

This book explores how to quickly find sequences of a few hundred nucleotides within a genome that may be made up of several billion, how to compare those sequences and how to reconstruct the complete sequence of a genome. It also discusses the problems of identifying bacteria in a given environment and predicting the structure of RNA based on its sequence.